MOTS-c 10mg
No published COA for this product · See all published COAs →
In stock · Ships within 1–2 business days by Canada Post (Express/Priority available at checkout)
About MOTS-c
MOTS-c is a 16-amino-acid peptide encoded within the 12S rRNA gene of mitochondrial DNA, with the sequence Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg. It belongs to a small group of mitochondrial-derived peptides, which are encoded by the mitochondrial genome rather than the cell nucleus.
Canada Research Labs supplies MOTS-c as 10mg of lyophilized powder in a 3 mL glass vial, packed and shipped from Ontario.
See our MOTS-c research overview.
Research background
MOTS-c was first described by Lee and colleagues (Cell Metabolism, 2015), who identified the peptide and examined its activity in cultured cells and mouse models, including effects on the folate cycle and activation of AMPK signaling. Later work by the same research group reported that MOTS-c can move into the cell nucleus under metabolic stress, which made it a subject of interest in research on communication between mitochondria and the nucleus.
The research field is young, and nearly all published work is preclinical. Researchers should review the primary literature directly when planning experiments.
References
- Lee C, et al. The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance. Cell Metabolism, 2015. PubMed
What you receive
- 10mg MOTS-c as a lyophilized powder
- 3 mL glass vial, sealed
- Shipped by tracked Canada Post from Ontario, within Canada only
Testing and documentation
Every lot we sell is tested by an independent laboratory using HPLC for purity and mass spectrometry for identity. Certificates for tested lots are published in our COA library, and each can be verified directly with the lab. Our guide explains how to verify a COA.
Handling
Lyophilized peptides are generally reconstituted with bacteriostatic water, sold separately. Storage guidance is listed in the Product Information section and FAQ.
Research use only
MOTS-c is supplied strictly as a reference material for in-vitro laboratory research by qualified professionals. It is not a drug, natural health product or cosmetic, and has not been authorized by Health Canada for any human or veterinary use.
Product Information
- Molecular Formula
- C101H152N28O22S2
- Molecular Weight
- 2174.64 Da
- Amount per vial
- 10mg
- Supplied as
- Lyophilized powder in a 3 mL glass vial
- Purity
- As shown in Certificate of Analysis
- Sequence
- Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg
Frequently asked questions
What is MOTS-c?
See our MOTS-c research overview .
What does one vial contain?
10mg of MOTS-c as a lyophilized powder, supplied for in-vitro laboratory research.
How is it tested?
Every lot is tested by an independent laboratory using HPLC for purity and mass spectrometry for identity. Certificates for tested lots are published in our COA library, and each can be verified directly with the lab.
How should it be stored?
Store sealed lyophilized vials at -20°C, protected from light and moisture. Short-term storage at 2–8°C is acceptable.
How fast does it ship?
Orders ship from Ontario within 1–2 business days by Canada Post standard shipping with tracking, or by Express/Priority if you select it at checkout. Shipping is free on orders over $300 CAD. We ship within Canada only.
How do I pay?
Interac e-Transfer. Payment instructions appear on your order confirmation.
Health Canada Notice - Research Use Only
These products are for in vitro use only. They have not been evaluated or approved by Health Canada for human or veterinary use. Sold strictly as reference compounds for in-vitro laboratory research conducted by qualified professionals in a controlled research setting. Not a drug, dietary supplement, food, cosmetic, or medical device, and not intended for the diagnosis, treatment, prevention, or cure of any condition in humans or animals. Resale, redistribution, or any human or animal administration is strictly prohibited.
