Research Articles and Guides
Literature overviews of the compounds we supply, written for researchers. Every article describes preclinical research only and is for informational purposes.
Welcome to the Canada Research Labs research blog, a hub for laboratory professionals, independent researchers, and students working with research peptides in Canada. Our articles cover peptide chemistry, storage and handling best practices, and comparisons between commonly studied compounds such as BPC-157, TB-500, CPB-1S, CPB-2T, and CPB-3R peptides.
All content here is published strictly for in-vitro research and educational use. None of our articles describe or endorse human or animal consumption. For questions about a specific compound, see our FAQ or review our Material Transfer Agreement.
Tesamorelin Research Overview: A Stabilized Full-Length GHRH Analog
A research overview of Tesamorelin: the discovery of GHRH, why native GHRH breaks down so quickly, how Tesamorelin's N-terminal modification works, and how it compares with shorter analogs.
Epitalon Research Overview: The Pineal-Derived Tetrapeptide
A research overview of Epitalon (Ala-Glu-Asp-Gly): its origin in pineal gland extracts, the telomerase studies it is known for, and the limits of a single-group literature.
NAD+ Research Overview: Redox Chemistry, Sirtuins and PARPs
A research overview of NAD+: its discovery, its role in redox reactions, the enzymes that consume it, how cells make it, and practical notes for laboratory work.
MOTS-c Research Overview: A Peptide Encoded in Mitochondrial DNA
A research overview of MOTS-c: how it was discovered, why a peptide encoded in mitochondrial DNA is unusual, and the laboratory models it has been studied in.
PT-141 (Bremelanotide) Research Overview: Melanocortin Pathways
A research overview of PT-141: its structure, its single terminal-group difference from Melanotan II, its melanocortin receptor profile, and why identity testing matters.
TB-500 Research Overview: Thymosin β4, Actin Binding and Cell Migration
A research overview of TB-500 and thymosin β4: structure, actin binding, the WH2 motif, key preclinical studies, and why the name TB-500 varies between suppliers.
AOD-9604 Research Overview: The Growth Hormone C-Terminal Fragment
A research overview of AOD-9604: its structure, why it is called both 177–191 and 176–191, its origins at Monash University, and the preclinical models it has been studied in.
KPV Research Overview: The α-MSH C-Terminal Tripeptide
A research overview of KPV (Lys-Pro-Val): its origin in α-MSH, PepT1 transport, the signaling pathways studied in cell models, and how it relates to the melanocortin system.
SS-31 (Elamipretide) Research Overview: Cardiolipin and the Inner Mitochondrial Membrane
A research overview of SS-31: its structure, how it reaches the inner mitochondrial membrane, its interaction with cardiolipin, and the laboratory models it is studied in.
Melanotan II Research Overview: A Non-Selective Melanocortin Agonist
A research overview of Melanotan II: the melanocortin receptor system, its cyclic structure, how it compares with Melanotan I and PT-141, and its use in receptor pharmacology.
GHK-Cu Research Overview: The Copper Tripeptide in Laboratory Studies
A research overview of GHK-Cu: its discovery, copper-binding chemistry, five decades of laboratory studies, and the difference between free GHK and the copper complex.
Semax Research Overview: The ACTH(4-10)-Derived Heptapeptide
A research overview of Semax: the ACTH fragment research it grew out of, its structure, the laboratory models it has been studied in, and the limits of its literature.
Ipamorelin in Canada: GH-Secretagogue Selectivity, Metabolic Signals, and the Research Landscape
Ipamorelin is a selective growth-hormone-releasing peptide that stimulates endogenous GH release while sparing cortisol and prolactin. Explore the research and why it is popular in Canada.
Selank Research Overview: The Tuftsin-Derived Heptapeptide
A research overview of Selank: its origin in tuftsin, the Pro-Gly-Pro extension, the laboratory models it has been studied in, and the limits of a mostly Russian literature.
CJC-1295 and Ipamorelin Research Overview: Two Receptor Pathways
How CJC-1295 and Ipamorelin act on two separate receptors, the difference between CJC-1295 with and without DAC, and what to check before comparing results.
BPC-157 Research Overview: Sequence, Origins and the Preclinical Literature
What BPC-157 is, where its research comes from, which preclinical models it has been studied in, and the open questions reviewers have raised about the literature.