Research Articles and Guides
Literature overviews of the compounds we supply, written for researchers. Every article describes preclinical research only and is for informational purposes.
Welcome to the Canada Research Labs research blog, a hub for laboratory professionals, independent researchers, and students working with research peptides in Canada. Our articles cover peptide chemistry, storage and handling best practices, and comparisons between commonly studied compounds such as BPC-157, TB-500, CPB-1S, CPB-2T, and CPB-3R peptides.
All content here is published strictly for in-vitro research and educational use. None of our articles describe or endorse human or animal consumption. For questions about a specific compound, see our FAQ or review our Material Transfer Agreement.
GHRH Analogs Compared: Sermorelin, CJC-1295 and Tesamorelin
Sermorelin, CJC-1295 (with and without DAC) and Tesamorelin compared: sequence length, stabilizing modifications, enzymatic stability and how researchers choose between them.
Tesamorelin Research Overview: A Stabilized Full-Length GHRH Analog
A research overview of Tesamorelin: the discovery of GHRH, why native GHRH breaks down so quickly, how Tesamorelin's N-terminal modification works, and how it compares with shorter analogs.
Net Peptide Content vs Purity: Why a Vial Isn't 100% Peptide
The difference between peptide purity and net peptide content, what else is in a lyophilized powder, how each is measured, and why it matters for laboratory calculations.
GLOW vs KLOW: Two Research Peptide Blends Compared
GLOW and KLOW blends compared: what is in each vial, how much of each component, the one peptide that separates them, and what researchers should know about blends.
Epitalon Research Overview: The Pineal-Derived Tetrapeptide
A research overview of Epitalon (Ala-Glu-Asp-Gly): its origin in pineal gland extracts, the telomerase studies it is known for, and the limits of a single-group literature.
Selank vs Semax: Two Russian Heptapeptides Compared
Selank and Semax compared: their parent peptides, sequences, the shared Pro-Gly-Pro design, the laboratory models each is studied in, and the limits of their literature.
HPLC and Mass Spectrometry Explained: What a Peptide Purity Number Means
How HPLC measures peptide purity and mass spectrometry confirms identity, what each result on a certificate of analysis tells you, and what neither one can tell you.
NAD+ Research Overview: Redox Chemistry, Sirtuins and PARPs
A research overview of NAD+: its discovery, its role in redox reactions, the enzymes that consume it, how cells make it, and practical notes for laboratory work.
BPC-157 vs TB-500: How the Two Research Peptides Differ
BPC-157 and TB-500 compared: structure, size, origin, research focus and literature, plus why they are often studied and sold together.
MOTS-c Research Overview: A Peptide Encoded in Mitochondrial DNA
A research overview of MOTS-c: how it was discovered, why a peptide encoded in mitochondrial DNA is unusual, and the laboratory models it has been studied in.
How to Order Research Peptides in Canada
A step-by-step guide to ordering from Canada Research Labs: choosing a product, checking the lot COA, checkout, payment and what happens after you order.
Research Peptide Glossary
Plain-language definitions of the terms used on research peptide labels, certificates of analysis and product pages, from acetate salt to WH2 motif.
Shipping Research Peptides Across Canada: Times, Tracking and Costs
How research peptide orders ship within Canada: Canada Post tracking, costs, transit times by region, winter shipping, and why domestic orders avoid customs.
Research Peptide Storage and Handling: Temperature, Light and Moisture
How to store lyophilized research peptides: temperature, light, moisture, freeze-thaw cycles, and which amino acids make some peptides less stable than others.
How to Choose a Research Peptide Supplier in Canada: 7 Checks
A practical checklist for evaluating Canadian research peptide suppliers: lot-matched COAs, third-party testing, purity data and domestic shipping.
PT-141 (Bremelanotide) Research Overview: Melanocortin Pathways
A research overview of PT-141: its structure, its single terminal-group difference from Melanotan II, its melanocortin receptor profile, and why identity testing matters.
TB-500 Research Overview: Thymosin β4, Actin Binding and Cell Migration
A research overview of TB-500 and thymosin β4: structure, actin binding, the WH2 motif, key preclinical studies, and why the name TB-500 varies between suppliers.
AOD-9604 Research Overview: The Growth Hormone C-Terminal Fragment
A research overview of AOD-9604: its structure, why it is called both 177–191 and 176–191, its origins at Monash University, and the preclinical models it has been studied in.
KPV Research Overview: The α-MSH C-Terminal Tripeptide
A research overview of KPV (Lys-Pro-Val): its origin in α-MSH, PepT1 transport, the signaling pathways studied in cell models, and how it relates to the melanocortin system.
SS-31 (Elamipretide) Research Overview: Cardiolipin and the Inner Mitochondrial Membrane
A research overview of SS-31: its structure, how it reaches the inner mitochondrial membrane, its interaction with cardiolipin, and the laboratory models it is studied in.
Melanotan II Research Overview: A Non-Selective Melanocortin Agonist
A research overview of Melanotan II: the melanocortin receptor system, its cyclic structure, how it compares with Melanotan I and PT-141, and its use in receptor pharmacology.
GHK-Cu Research Overview: The Copper Tripeptide in Laboratory Studies
A research overview of GHK-Cu: its discovery, copper-binding chemistry, five decades of laboratory studies, and the difference between free GHK and the copper complex.
Semax Research Overview: The ACTH(4-10)-Derived Heptapeptide
A research overview of Semax: the ACTH fragment research it grew out of, its structure, the laboratory models it has been studied in, and the limits of its literature.
Ipamorelin in Canada: GH-Secretagogue Selectivity, Metabolic Signals, and the Research Landscape
Ipamorelin is a selective growth-hormone-releasing peptide that stimulates endogenous GH release while sparing cortisol and prolactin. Explore the research and why it is popular in Canada.
Selank Research Overview: The Tuftsin-Derived Heptapeptide
A research overview of Selank: its origin in tuftsin, the Pro-Gly-Pro extension, the laboratory models it has been studied in, and the limits of a mostly Russian literature.
CJC-1295 and Ipamorelin Research Overview: Two Receptor Pathways
How CJC-1295 and Ipamorelin act on two separate receptors, the difference between CJC-1295 with and without DAC, and what to check before comparing results.
BPC-157 Research Overview: Sequence, Origins and the Preclinical Literature
What BPC-157 is, where its research comes from, which preclinical models it has been studied in, and the open questions reviewers have raised about the literature.
Mannitol vs Mannitol-Free Peptides
Understanding the difference between mannitol and mannitol-free peptides. Learn about the role of mannitol in peptide stability and which option is right for your research needs.
How to Verify a Certificate of Analysis
How to read a certificate of analysis and confirm it directly with the testing laboratory.